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Human Growth Hormones: Both Sides of the Coin

As mentioned before, Turner’s Syndrome patients must undergo different treatments through their lives. One of the most common treatments used is the Human Growth Hormone, which is used only for growth. Not only does the Human Growth Hormone have benefits, it also has its downfalls. Human growth hormones are used to help manage the short stature that patient’s with Turner’s Syndrome experience. A growth hormone is a hormone that is produced in the pituitary gland to stimulate the release of somatomedin, a hormone that is released by the liver, to stimulate growth. Human growth hormones started to be used to manage Turner’s Syndrome in 1983, and were approved by the FDA in 1997, after extensive studies. The benefits of the use of the hormones vary differently from patient to patient. Some patients have no change in height, where other patients have gained up to 11.9 centimeters in their height. The reasons for this are unknown however, because of the differences of age among the patients and the amount of dosage used on the patients were varied.

This link is a video of a physician that supports the use of Human Growth Hormones.

This form of treatment is only used for short term management because of the different factors that are associated with the treatment. During short term treatment, it has been found that there is an increase in blood pressure and insulin resistance; however both go back to normal when the treatments cease.  It is not good for long term treatment. Long term treatment can lead to cardiac problems, especially ones associated with the aortic-root diameter and have an unknown risk of causing Type II Diabetes. So far, there is no established amount for the dosage and frequency at which the treatment should be used. There are many unknown variables when it comes to the use of Human Growth Hormones. This is also a very expensive form of management because it is estimated that the cost for each centimeter of height gained is $29,000. Many physicians have opposing viewpoints on the usage of Human Growth Hormones. Some physicians believe it is a wonderful thing to use. Other physicians believe it should not be used.

This video is an interview with Dr. Andrew Hoffman, one of the leading researchers in America, talking about Human Growth Hormones and his opinon on them. He also includes athletes in his interview.

Sources:

http://www.nejm.org/doi/full/10.1056/NEJMra030360

 

5 responses to “Human Growth Hormones: Both Sides of the Coin

  1. maherc

    December 1, 2012 at 11:26 pm

    There is a lot of good information in this page, but there is a lot of text. I would maybe split up the large amount of text by putting the picture in the middle of the page rather than at the bottom after all of the information.

     
  2. kzzj

    December 3, 2012 at 2:49 am

    Maybe try to break up the large paragraphs into chunk through adding pictures in between to help keep the concentration of the reader.

    -Joshua Pohl

     
  3. Nemanja Vukovic

    December 4, 2012 at 2:34 pm

    I thought that it was effective that you guys gave “both sides of the coin”. I think that readers would like to know what the drugs are about, but for those that are considering taking the drug, understanding the repercussions would be more vital. So I would definitely keep the “both sides of the coin” idea. However, sometimes it seems as if you guys bring up an important detail but don’t further explain it. I personally would’ve enjoyed knowing why age difference plays a role in the amount that the patients grew, or why there hasn’t been a standardized dose for certain ages. It just ended off with “The reasons for this are unknown however, because of the differences of age among the patients and the amount of dosage used on the patients were varied.”

     
  4. tfischer42

    December 4, 2012 at 11:16 pm

    A great section that deals well with both sides of an argument. Very well done! A suggestion – you may wish to clarify whether HGH is a treatment for the syndrome as a whole, or simply one or two symptoms of the disease.

     
  5. biowikiproject

    December 5, 2012 at 12:17 pm

    I like the two different takes on the treatment. This really helpful in understanding the pros and cons for the treatment. Is this the best treatment there is so far? What are some of the other treatments?

     

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